When we are feeling down, irritable, angry or down right miserable, we usually have good reason. Life can sometimes cause anguish. You may experience events, such as unexpected circumstances, loss, relationships turning out badly, finding that circumstances are worse than you expected and being separated from loved ones that leave you in emotional turmoil. At times, it can feel like you barely pick yourself up from one emotional crisis when the next hits.
Source: http://www.mentalhelp.net/poc/view_doc.php?type=doc&id=46780&cn=110
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